Germline PV of other genes of the HR, especially PALB2, CHEK2, and ATM, were found in 0.5–1.5% of patients with unselected breast cancers [12,18,19,20,21,39,40,41,42,43,47,48,49] (Table 1), and were obviously more frequent among patients with family breast cancer history [18,50,51,52,53]. Here, CHEK2 is linked to breast carcinoma.