Elevated expression of CXCR2 ligands (CXCL1, 2, 3, 5, 6, 7, and 8) is observed in various tumor types, such as lung cancer [158,159,160], hepatocellular carcinoma [161], renal cell carcinoma [162], and melanoma [72]. This evidence concerns the gene CXCL1 and neoplasm.