Tumour-infiltrating cells are known to take part in the pathogenesis of lung adenocarcinoma [88], and TIMER analysis showed that high AHNAK2 expression was associated with more central memory CD4+ and CD8+ T cells, but reduced the expression of activated B cells, activated CD8+ T cells, eosinophils, immature B cells, DC cells, and all of their markers [65]. Here, CD4 is linked to neoplasm.