AHNAK2 knockdown in M17 and SP6.5 cells suppressed cell proliferation, migration, and invasion, while also inhibiting the activation of the phosphatidylinositol 3-kinase (PI3K) signalling pathway [53], which is known to be part of the PI3K-AKT-mTOR pathway that controls metabolism, proliferation, growth, and survival and is one of the most dysregulated pathways in cancer [75]. This evidence concerns the gene AHNAK2 and cancer.