ATRX and breast cancer: LOH at 5q21 in 0% of TCs and 25% of ACs [37]LOH of 17p13 in 45% of ACs and 10% of TCs [38].LOH of 3p in 40% of TCs, 73% of ACs [39]. LOH ATRX protein in 20% of BC [40], more common in AC than in TC.