A similar observation has also been made by Sody et al. [70]; blocking CXCR2 using AZD5069 profoundly inhibited recruitment of Tumor-Associated Neutrophils (TANs) into peripheral region surrounding solid tumor cell lesions within a mouse model, while intratumoral infiltration was only transiently attenuated and rebounded at later time points. Here, CXCR2 is linked to neoplasm.