CXCL2 is highly expressed in HCC [129], and engineered overexpression of the CXCR2L receptor (CXCR2) on GPC3-CAR-T cells was shown to enhance CAR-T infiltration and expansion at the tumour site in a xenogeneic HCC model [129]. Here, CXCR2 is linked to hepatocellular carcinoma.