SLC2A1 and osteosarcoma: Fewer studies have examined GLUT-1 expression in canine and human osteosarcomas leading to conflicting results [64,65,66] ranging from no statistical correlation between GLUT-1 expression and DFS, survival time or percentage of necrosis in dogs [64], to strong GLUT-1 staining in both primary sites and metastases [65] and association with shorter DFS [66].