M/A treatment of glioblastoma cells induced a significant dose-dependent decrease in the values of the parameters characterizing mitochondrial functionality and cellular redox homeostasis: mitochondrial membrane potential, NADH, NAD+, oncometabolite succinate, steady-state ATP amount, total intracellular glutathione, total cellular reducing capacity, and tNOX (Figure 3E). The gene discussed is ENOX2; the disease is glioblastoma.