Pubmed search for “MKK3 & cancer” (https://pubmed.ncbi.nlm.nih.gov/?term=%22mkk3+%26+cancer%22&sort=pubdate, (accessed on 25 November 2021) or “MAP2K3 & cancer” (https://pubmed.ncbi.nlm.nih.gov/?term=%22MAP2K3+%26+cancer%22, (accessed on 25 November 2021) identified 158 and 102 manuscripts from 1996 to 2021, respectively. This evidence concerns the gene MAP2K3 and cancer.