MAP2K3 and metastatic malignant neoplasm in the lymph nodes: They showed that high expression of MAP2K3 was significantly correlated with CA125 level (p < 0.001), tumor size (p = 0.001), lymph node metastasis (p = 0.008), depth of myometrial invasion (p < 0.001), and FIGO stage (p < 0.001), indicating MKK3 as a poor prognostic biomarker [54].