CD4 and neoplasm: These changes concerned, in particular, increases in the presence of CD3+ CD69+ T cells (by a factor of 1.51), CD4+ CD69+ T cells (by a factor of 3.42), CD8+ CD69+ T cells (by a factor of 2.50), and CD8+ CD25+ T cells (by a factor of 1.37) in the tumor vs. the lymph node samples.