MYC and neoplasm: Notably, among the five major NKG2DL, MICB was the main NKG2DL regulated by MYC in H2227 cells (Figure 2C), while MICA was the main one regulated by MYC in H446 cells (Figure S2C), indicating that the regulatory pathways of the same NKG2DL may be different in distinct tumor cells, which required to be further studied.