However, cell death due to membrane-damage, i.e., Annexin V+FVD+ cells, showed a pattern consistent with the differential reduction of plasma cells and plasmablasts in schistosomiasis-diseased Vac+Sm+ mice with an equally recapitulative restoration by death rate reduction in Vac+Sm+PZQ+ mice. Here, ANXA5 is linked to schistosomiasis.