The overall negative predictive value (NPV) is 79.0% (CI 95%: 77.0–82.0%) and between 67.0% (CI 95%: 55.0–77.0%, CLINITEST Rapid COVID-19 Antigen Test) and 85.0% (CI 95%: 76.0–92.0%, Vazyme SARS-CoV-2 Antigen Detection Kit) for the individual Ag-RTDs. This evidence concerns the gene RENBP and COVID-19.