MMP16 and allergic asthma: For example, in asthmatic children, miR-29c is down-regulated in blood monocytes, and the miR-29c/B7-H3 axis can regulate acute allergic asthma attack by modulating Th2/Th17 cell differentiation [34]; another study reports that miR-192-5p relieves asthmatic airway remodeling and autophagy through targeting ATG7 and MMP-16 [35].