Indeed, STAT5 binding was significantly increased from 8.5% of all nonregulated genes to 14.9% of the 398 regulated genes in Pax5Jak2/+ B‐ALL tumors (Fig 7G), which was also confirmed by GSEA analysis (Appendix Fig S7I). The gene discussed is STAT5A; the disease is precursor B-cell acute lymphoblastic leukemia.