For example, Elliott et al. proved that Ezrin was necessary for breast cancer metastasis [18], Elzagheid et al. verified that Ezrin expression was involved in poor survival in colorectal cancer [19], and Xu et al. revealed that Ezrin could be a prognostic factor and a predictor of potential lung metastasis in osteosarcoma [20,21]. Here, EZR is linked to osteosarcoma.