Fortunately, we not only found that LINC00525, which was highly expressed in colorectal cancer cells, promoted the proliferation of colorectal cancer cells in vivo and in vitro but also found that LINC00525 activated HIF-1α through the miR-338-3p/UBE2Q1/β-catenin axis to enhabcehypoxia-enhanced glycolysis in colorectal cancer. Here, LINC00525 is linked to colorectal cancer.