The differentiated/proliferative to mesenchymal/invasive phenotypic switch in melanoma is accompanied by another switch that involves the expression of the so‐called epithelial‐to‐mesenchymal transition‐inducing transcription factors (EMT‐TFs), and that may be regulated by TGFβ (Pedri et al, 2021). The gene discussed is TGFB1; the disease is melanoma.