FSCN1 and melanoma: Our study shows that mechanistically the miR‐143/‐145 cluster functions in melanoma cells through targeting the cytoskeletal regulator FSCN1, one of the best hits identified by our screening, confirming previous studies indicating that FSCN1 is a direct target of both mature miRNAs (Kano et al, 2010; Liu et al, 2012).