Interestingly, we found an upregulation of NFKB Inhibitor Alpha (NFKBIA) and NFKB Inhibitor Zeta (NFKBIZ) genes, both with inhibitory functions upon NFKB, which may be related to the high level of inflammation in T1D patients [41]. This evidence concerns the gene NFKB1 and type 1 diabetes mellitus.