CRP and acute kidney injury: Septic shockn = 111Multicentre, double-blind, randomized clinical trialPrimary outcomes: ΔSOFA scoreSecondary outcomes: 7-day, 28-day, 90-day, in-hospital and ICU mortality, shock reversal, vasopressor free days, vasopressor dose, duration of mechanical ventilation, ventilator-free days, AKI, RRT, RRT-free days, LOS ICU, ICU-free days, hospital LOS, reduction of C-reactive protein (CRP) and procalcitonin for 72 h