ACE and rheumatoid arthritis: In the mixed cohort of 51 arthritis (RA+AS) patients, serum ACE concentration significantly increased after 6 M (166.7 [124–232] ng/mL; p = 0.003) and 12 M of treatment (183.4 [121–222] ng/mL; p < 0.001) compared to B (142.7 [88–176] ng/mL).