In HCC (Tu et al., 2019; Wang et al., 2019), LINC00707 knockdown inhibits HCC cell proliferation, cell cycle progression, and colony formation via depression of the ERK/JNK/AKT signaling pathway in Hep3B and SNU449 cells or via regulation of miR-206 and CDK14 in vivo and in HepG2 and Huh7 cells. This evidence concerns the gene AKT1 and hepatocellular carcinoma.