Moreover, Liang et al. transfected HEK293 cells with Target-Her 2-Lamp2-GFP (THLG) and purified their derived exosomes, which when loaded with anti-cancer drug 5-Fluorouracil (5-Fu) could directly target Her 2 positive colon cancer cells and inhibit the growth of colon cancer in mice (Liang et al., 2020). This evidence concerns the gene LAMP2 and colonic neoplasm.