For tumor antigen-targeting we used epithelial cell adhesion molecule (EpCAM, CD326) (Das et al., 2015) and human epidermal growth factor receptor 2 (HER2, CD340) (Siena et al., 2018); both are up-regulated in CRC, but not in healthy cells, and therefore represent CRC markers. The gene discussed is ERBB2; the disease is colorectal carcinoma.