CAV1 and posterior cortical atrophy: Mechanistically, CAV1-deficient fibroblasts were shown to foster RT resistance of PCa cells by allocating CAV1-dependent apoptosis inhibiting proteins to the tumor cells, e.g., the p53-inducible cell survival factor TRIAP1 (TP53-regulated inhibitor of apoptosis 1, also known as p53CSV) (13).