CAV1 and posterior cortical atrophy: Here we used LNCaP PCa cells stably expressing either wildtype CAV1, the phosphorylation-deficient CAV1 Y14F mutant or the CAV1 P132L mutant known to ‘mis-localize’ CAV1 away from the plasma membrane in order to investigate how a proper CAV1 localization and functionality impacts on the RT response of malignant prostate epithelial cells.