Further, we noticed cisplatin induced IAPs mRNA/protein expression including c-IAP1, c-IAP2 and survivin and an immune modulator CD70 in A2780CP cells, whereas 3PO could abolish their mRNA/protein induction, suggesting 3PO could sensitize ovarian cancer cells to cisplatin possibly through the modulation of c-IAP1, c-IAP2, survivin and CD70 mRNA expression. The gene discussed is BIRC5; the disease is ovarian cancer.