In this study, we aim to quantify the relationship between diabetic retinopathy and urine albumin excretion and to correlate the urinary albumin excretion (normoalbuminuria, microalbuminuria, macroalbuminuria) with the severity and grade (mild, moderate, severe NPDR or PDR) of diabetic retinopathy. The gene discussed is ALB; the disease is diabetic retinopathy.