GSEA enrichment analysis revealed that BGN-related DEGs were significantly enriched in collagen formulation (Nissen et al., 2019), immunoregulatory interactions between a lymphoid and a non-lymphoid cell (Sautès-Fridman et al., 2019), focal adhesion (Eke and Cordes, 2015), ECM glycoproteins (Mohan et al., 2020), Wnt signaling (Bugter et al., 2021), and signaling by VEGF (Apte et al., 2019), which were significantly related to the tumor. The gene discussed is VEGFA; the disease is neoplasm.