BGN expression was remarkably correlated with histologic grade (Figure 5A, GI&G2 vs. G3, p < 0.001), histologic type (Figure 5B, Diffuse type vs. Tubular type, p < 0.001), histologic stage (Figure 5C, stage I vs. stage II and stage I vs. stage III, p < 0.001), T stage (Figure 5D, T1 vs. T2, T1 vs. T3, and T1 vs. T4, p < 0.001) and Helicobacter pylori (HP) infection (Figure 5G, yes vs. no, p < 0.05) in gastric cancer (GC). This evidence concerns the gene BGN and Helicobacter pylori infectious disease.