BCR and chronic myelogenous leukemia, BCR-ABL1 positive: Synonymous to CML is the BCR-ABL fusion oncoprotein resulting from the Philadelphia chromosome, which is a direct result of translocation between chromosome 9 and 22 (Trela et al., 2014; Chan et al., 2017; Chopade and Akard, 2018; Hsieh et al., 2021).