In the human populations, the CCR5-Δ32 allele was not significantly associated with neurodegenerative dementias, however, an earlier age of onset of neurodegenerative disease was observed in carriers of the CCR5-Δ32 allele, suggesting that the deletion may have a detrimental effect in the context of neurodegeneration (132). Here, CCR5 is linked to neurodegenerative disease.