To visualize the networked host response, we first constructed correlation matrices for Mcpt4-/- and Mcpt4+/+ mice to identify significant positive and negative relationships over time between parasitemia and blood 16S copies with ileal MC numbers, levels of plasma and ileal cytokines and chemokines, plasma IgE, plasma Mcpt1, MPO and NE (Figure S3). This evidence concerns the gene IGHE and parasitic infectious disease.