Among the ten identified genes, ALB (51, 52), CDKN3 (53), TUBB3 (54, 55), DRD5 (56, 57), PTGS2 (58), and OPCML (59, 60) were reported to be associated with the prognosis of PCA, while the potential roles of SLC25A27, AK5, PLP1, and GUCY2C in PCA remained largely unexamined. The gene discussed is AK5; the disease is posterior cortical atrophy.