We also observed that B. dorei-induced higher expression of IFN-γ was only observed at day 3 p.i. but not at day 7 p.i. compared with control infected mice, which suggests that B. dorei’s anti-influenza effect may be related to its timely action in enhancing antiviral response in the early stage of infection while preventing excessive and long-lasting inflammatory damage. This evidence concerns the gene IFNG and infection.