Figure S3B illustrates the proportion of GBM patients with the indicated clinical status and molecular traits in the three groups with different non-m6A RNA modification patterns. Patients over 60 years old and those who were alive at the last follow-up were primarily in Cluster_C, while patients with IDH wild-type status and no MGMT methylation were mainly found in Cluster_B (Figure S3B). The gene discussed is IDH1; the disease is glioblastoma.