GH1 and hypogonadism: Patients with hypogonadism were younger (p<0.001), fatter (p=0.001), and more likely to be males (p<0.001), had larger and more invasive tumors (p<0.001) and greater ki-67 index (p<0.01), and had higher levels of GH (p<0.001), GH nadir (p=0.001) and IGF-1 (p=0.007), compared to patients with normal gonadal function.