ERBB2 and breast carcinoma: Breast cancer is divided into different types depending on its origin, and the prognosis and treatment options for each type are generally based on the tumor-node-metastasis staging, lymphovascular spread, histological grade, HR status, ERBB2 (formerly HER2 or HER2/neu) overexpression, comorbidities, menopausal status, and age (Onitilo et al., 2009).