BAX and gastric cancer: In addition, AKT and mTOR have been reported to be targeted via miR-495 overexpression of miR-495, which could prevent the growth in addition to induce the apoptosis of GC cells through blocking of PI3K/AKT/mTOR, which altered Bax, caspase-3/-9, and cyclin D1 expression (Ouyang et al., 2021).