Antiautophagy tumor suppressor, miR-30a, upsurges sensitivity to imatinib (IM) in gastrointestinal stromal tumor (GIST) cells alone with mouse xenograft models with specific target of miR-30a in association with beclin-1–driven autophagy in IM-resistant cells such as GIST-882 than the sensitive GIST-1 cell line (Shao et al., 2020), but counterintuitive that miR-183 could contribute to GC suppression (Li et al., 2019). This evidence concerns the gene BECN1 and neoplasm.