Ramentaceone, a naphthoquinone isolated from Drosera rotundifolia L., was reported to induce BC cell apoptosis by inhibiting the PI3K/AKT signaling pathway, which was highly correlated with upregulated Bax and Bak expression, downregulated Bcl-2 expression, and inhibition of PI3K and AKT phosphorylation (Kawiak and Lojkowska, 2016). The gene discussed is BCL2; the disease is breast cancer.