The presence of PD and LY blocked the reduction of cleaved caspase-3 [PD: Welch’s ANOVA: W(3,5.705) = 10.88, p = 0.0088; LY: Welch’s ANOVA: W(3,5.379) = 8.958, p = 0.0159] (Figure 7B) and the increase of proBDNF [PD: Welch’s ANOVA: W(3, 6.466) = 5.361, p = 0.0351; LY: Welch’s ANOVA: W(3,6.456) = 5.734, p = 0.0303] (Figure 7C) mediated by PACAP in STHdhQ111/Q111 cells. This evidence concerns the gene BDNF and Parkinson disease.