In view of this, Ofengeim et al. (2017) found that Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) expression can activate the microglial response in AD, while Keaney et al. (2019) has suggested that tyrosine kinase can regulate microglia phagocytosis in AD. The gene discussed is RIPK1; the disease is Alzheimer disease.