Future studies investigating the LRRK2-relevant behavioural changes in KI mice may aim to use a panel of common tests on different aspects of PD motor and non-motor symptoms: bar and drag test, stepping test or pole test for measuring akinesia/bradykinesia; rotarod test for measuring balance, strength and coordination; tail-suspension test or forced swim test for assessing depression and behavioural despair [140]. Here, LRRK2 is linked to Parkinson disease.