PGRMC1 and glioblastoma: Additionally, AG-205 or PGRMC1 siRNA treatment notably improved UTMD-induced radiosensitization of glioblastoma cells, and PGRMC1 overexpression markedly inhibited UTMD-induced radiosensitization of glioblastoma cells (P < 0.05, Fig. 8a–d and Additional file 1: Fig. S2).