Previous studies have shown that the highly expressed lncRNA DGCR5 can regulate the expression of multiple target genes, such as estrogen receptor 1, checkpoint kinase 1, fibroblast growth factor 2, sterile alpha motif domain containing 5 (Samd5), ephrin-A3, and forkhead box P3, thereby inhibiting the proliferation and lymphatic metastasis of triple-negative breast cancer (TNBC) cells [8]. Here, SAMD5 is linked to triple-negative breast carcinoma.