CA9 and congenital dyserythropoietic anemia: The results showed that the low expression of CA9 in the disease may induce CDA by activating amino acid degradation, fatty acid metabolism, peroxidase and oxidative phosphorylation, while the overexpression of CA9 activated ‘VASCULAR SMOOTH MUSCLE CONTRACTION’ and ‘ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY ARVC’ (Figure S1A).