PNPLA2 and hydrops fetalis: Comparable to the results observed after acute lipid load, Atgl iTg mice showed accelerated cholesterol absorption from the intestinal lumen after 5 weeks of HF/HCD feeding, as indicated by a 1.6-fold increased secretion of the radioactive tracer into the bloodstream (Fig. 5A) and a 37% decrease in fecal excretion (Fig. 5B).