More importantly, using the standard cutoff of hs-cTnI (99th percentile) might underestimate the extent of cardiac damage in non-severe patients with COVID-19, and the cutoff of hs-cTnI should be redefined (e.g. ≥ 5 ng/L) to identify patients who are at high risk of cardiac damage. The gene discussed is TNNI3; the disease is COVID-19.