TNF and myalgic encephalomeyelitis/chronic fatigue syndrome: The results of Western blotting, RT-qPCR, and ELISA, all revealed that Ang II markedly facilitated the expressions of NLRP3, TNF-α, and IL-6, while miR-135a-5p mimic inhibited the promoting role of Ang II on the release of inflammatory factors (P < 0.05, Figure 3(c-e)), which highlighted the ability of miR-135a-5p to suppress Ang II–induced inflammation of CFs.