Wetli et al. investigated exon 12,14 and 18 mutations by sequence analysis in 209 Wilms tumor cases, and did not detect the PDGFR alpha mutation; they concluded that PDGFR alpha immunostaining was not reliable (19). Epithelial, stromal, and blastemal components of the 16 WT cases of our study showed immunopositivity with varying intensity and extent. Here, PDGFRA is linked to Nephroblastoma.