Of the PSMA-avid lymph and distant lesions found in this study’s high-risk PCa group, 34 patients (51.5%) had suspicion for pelvic LN metastases, 21 (31.8%) had suspicion for bone metastases on 68Ga-PSMA PET/CT, and 17 individuals had both bone and LN metastases. Here, FOLH1 is linked to posterior cortical atrophy.